On this episode of ID the Future, biochemist Michael Behe and host Andrew McDiarmid discuss the anti-malarial drug chloroquine, now being investigated as a treatment for COVID-19, and how it may work on the cellular level against the coronavirus. The same drug was featured in Behe’s 2007 book The Edge of Evolution, as part of his demonstration that evolution has strict limits: It can do adaptive work for organisms with single mutations, but if just two coordinated mutations are required at once, evolution’s random processes have great difficulty even with natural selection helping them along. In cases where population sizes are enormous, as with malaria, it can eventually overcome the need for two simultaneous and coordinated mutations, but only just barely. Because the odds go up exponentially, three simultaneous coordinated mutations may be beyond the edge of evolution. What does all this bode for chloroquine and the coronavirus? Listen in as McDiarmid and Behe discuss.