ID the Future Intelligent Design, Evolution, and Science Podcast
Topic

protein folding problem

ribosome-translating-mrna-into-a-polypeptide-chain-stockpack-adobe-stock
Ribosome translating mRNA into a polypeptide chain
Ribosome translating mRNA into a polypeptide chain Photo by Juan Gärtner on Adobe Stock

Orphan Proteins Spell Trouble for AlphaFold 2

On this ID the Future, philosopher of biology Paul Nelson further explores AlphaFold 2, a cutting edge computer program from Google’s DeepMind designed to rapidly suss out important secrets in the realm of proteins, indispensable molecular biological workhorses that come in thousands of different shapes and sizes. Nelson enthuses about AlphaFold 2 but also explains why he is convinced that AlphaFold’s creators have hit a series of immovable obstacles. The watchword here—orphans. Tune in to learn what these mischievous orphan proteins are about, and what they suggest for AlphaFold, evolution, and intelligent design.

protein
Chain of amino acid or bio molecules called protein - 3d illustration
Chain of amino acid or bio molecules called protein - 3d illustration Photo by Christoph Burgstedt on Adobe Stock
Chain of amino acid or bio molecules called protein - 3d illustration

Powerful Protein Folding Algorithm AlphaFold Foiled by Singletons

Today’s ID the Future spotlights AlphaFold, an artificial intelligence program in the news for its impressive breakthroughs at predicting a protein’s 3D structure from its amino acid sequence. Philosopher of Biology Paul Nelson walks listeners through the importance of this “amazing breakthrough,” as he describes it in a recent Evolution News article; but don’t uncork the champagne bottles just yet. The reason, according to Nelson, is that while proteins, protein sequences, and protein folding promise to reveal much that is still mysterious in molecular biology, we now know that biological information involves far more than just an organism’s proteome—that is, far more than the full suite of proteins expressed by an organism. Nelson uses analogies to manmade machines and cognates Read More ›