ID the Future Intelligent Design, Evolution, and Science Podcast
Topic

early earth atmosphere

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Single helix RNA, Epigenetics concept

Minimal Replication Fidelity: Another Problem for the RNA World Hypothesis

The RNA world is proposed by some to explain how early life began before DNA. But is RNA capable of maintaining a life-friendly self-replication rate? On this ID The Future, host Andrew McDiarmid welcomes back Dr. Jonathan McLatchie to discuss another headache for the RNA world scenario. Before a trial and error process like natural selection can even get started, self-replicating molecules must have a minimal accuracy rate to copy genetic material effectively. The required fidelity rate is estimated to be 2%. Any error rate higher than that results in error catastrophe for organisms. The average error rate in RNA copying is estimated to be around 17%, vastly higher than the estimated maximum error threshold for survival. McLatchie explains the implications of this for chemical evolutionary theories like the RNA world hypothesis. He also explains how a Bayesian approach to this evidence can provide us with the likeliest explanation for the origin of biological life. "The sorts of features that we observe in life are not particularly surprising if we suppose that a mind is involved," says McLatchie. But things like minimal self-replication fidelity are wildly surprising on a naturalistic hypothesis. Read More ›
Photo by @plqml

Walter Bradley on the Newly Expanded Mystery of Life’s Origin

On this episode of ID the Future, Robert J. Marks interviews Walter Bradley, co-author of the seminal 1984 ID book The Mystery of Life’s Origin, now being released in a revised and expanded edition with updates from multiple contributors discussing the progress (or lack of it) in origins science in the 35 years since the book’s original publication. In this first of two podcasts, Bradley discusses the history of the attempts to explain life’s origin naturalistically, and how the three authors of the 1984 book came together to shake up the world of origin-of-life science.